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Formulation, Characterization, and Stability of Protein Drugs Case Histories (Pharmaceutical Biotechnology) (Pharmaceutical Biotechnology) by

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  • 11 Currently reading

Published by Springer Verlag .
Written in English

Subjects:

  • Pharmaceutical Chemistry,
  • Medical,
  • Medical / Nursing,
  • Science/Mathematics,
  • Pharmacy,
  • Science / Biological Sciences,
  • Medical / Pharmacology,
  • Medical : Pharmacy,
  • Peptide drugs,
  • Pharmacology,
  • Protein drugs,
  • Proteins,
  • analysis

Book details:

Edition Notes

ContributionsRodney Pearlman (Editor), Y. John Wang (Editor)
The Physical Object
FormatHardcover
Number of Pages460
ID Numbers
Open LibraryOL9541875M
ISBN 100306453320
ISBN 109780306453328

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Leading scientists offer detailed profiles of ten protein drugs currently in development. The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability. This ready reference also features recent data and an abundance of previously unpublished information. The in-depth coverage includes a highly useful compendium of. Leading scientists offer detailed profiles of ten protein drugs currently in development. The case histories of these important new compounds are described from the perspective of their formulation, characterization, and stability. This ready reference also features recent data and an abundance of previously unpublished information. Formulation, Characterization, and Stability of Protein Drugs, Rodney Pearlman and Y. John Wang, eds., Plenum Press, New York, Michael F. Powell. 1. INTRODUCTION. The accurate prediction of protein stability under pharmaceutical formulation conditions is one of the more challenging goals in protein formulation. Protein Stability and Characterization. Native ESI MS also allows the interactions of protein drugs with their therapeutic targets and other physiological partners to be monitored using simple Author: Atanas Koulov.

This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar­ keted or are under clinical testing. In previous volumes of this series,funda­ mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise.5/5(1). Stability and Characterization of Protein and Peptide Drugs by Rodney Pearlman, , available at Book Depository with free delivery worldwide. Nonionic surfactants are often used in protein formulations to reduce interfacial stress and prevent protein denaturation, aggregation, and adsorption loss (Lee et al., ).Thus, if interfacial stress is a stability concern for a particular protein molecule, then use of a nonionic surfactant is a good first step in mitigating this problem. Nguyen TH, Ward C () Stability characterization and formulation development of Alteplase, a recombinant tissue type plasminogen activator. In: Wang YJ, Pearlman R (eds) Stability and characterization of protein and peptide drugs: Case Histories, Plenum Press, New York, pp 91 – Author: C. R. Middaugh, R. Pearlman.

Parenteral formulations of proteins and peptides: stability and stabilizers Article (PDF Available) January with 1, Reads How we measure 'reads'. Stability and Characterization of Protein and Peptide Drugs Stability and Characterization of Protein and Peptide Drugs Case Histories. Editors: Pearlman, Rodney, Wang, Y. John (Eds.) Stability Characterization and Formulation Development of Alteplase, . SCREENING APPROACH TO THE CHARACTERIZATION AND FORMULATION OF BIOPHARMACEUTICALS Sangeeta B. Joshi, Akhilesh Bhambhani, Yuhong Zeng, and C. Russell Middaugh 9 FLUORESCENCE AND PHOSPHORESCENCE METHODS TO PROBE PROTEIN STRUCTURE AND STABILITY IN ICE: THE CASE OF AZURIN Giovanni B. Strambini 10 . Stability and Characterization of Protein and Peptide Drugs Case Histories. Editors (view affiliations) Y. John Wang; Rodney Pearlman Search within book. Front Matter. Pages i-xxi. PDF. Michael J. Hageman. Pages Stability Characterization and Formulation Development of Alteplase, a Recombinant Tissue Plasminogen Activator. Tue H.