Includes bibliographical references and index.
|Statement||Erin C. Donnelly and Arthur M. Dixon, editors|
|Series||Immunology and immune system disorders, Immunology and immune system disorders|
|LC Classifications||QR189.5.D53 D64 2011|
|The Physical Object|
|Pagination||x, 202 p. :|
|Number of Pages||202|
|LC Control Number||2011012604|
Plasmids are circular deoxyribonucleic acid (DNA) vectors that can be used as vaccines to prevent various types of diseases. These plasmids are DNA platforms that are usually composed of a viral promoter gene, a gene coding resistance to antibiotics, a bacterial origin of replication gene and a multiple cloning site (MCS) for a transgenic region, where one or several genes of Author: Leonardo A. Gómez, Angel A. Oñate. In DNA Vaccines: Methods and Protocols, state-of-the-art review articles by leading experts summarize how to develop and employ the highly promising new DNA vaccines, what clinical results can be expected from their use, and what is known about how they work. Key topics range from vaccine design and construction to preparation and delivery Format: Paperback. John J. Donnelly, Margaret A. Liu, in Encyclopedia of Immunology (Second Edition), DNA vaccines encoding proteins of M. tuberculosis have been shown to be effective for generating the desired cellular responses and protection from challenge. This model has been instructive, in that in this system the mycobacterial protein is made by the mammalian host cell rather than by the . Excipients Included in U.S. Vaccines, by Vaccine. In addition to weakened or killed disease antigens (viruses or bacteria), vaccines contain very small amounts of other. ingredients – excipients. Some excipients are added to a vaccine for a specific purpose. These include: Preservatives, to prevent contamination. For example, thimerosal.
DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. The global DNA vaccines market is segmented based on type, technology, application, end user and geography. Based on type, the market is further segmented into human DNA vaccines and animal DNA vaccines. Based on technology, the DNA vaccines market is further segmented into DNA vaccine technology and DNA delivery technology. Tanja D. de Gruijl, Rieneke van de Ven, in Advances in Cancer Research, Combining Ad vaccines with non-Ad vaccines. A different way to circumvent the negative effects of Ad vaccine-neutralizing antibodies is to combine AdVs with protein, DNA or RNA vaccines, bacterial vaccines, or other viral vectors based on, for example, herpes virus, pox virus, vesicular . DNA Vaccines: Methods and Protocols, Third Edition explores innovative approaches and technologies used to design, deliver, and enhance the efficacy of DNA ing applications which should be of great value in moving vaccines from research to clinic, this detailed volume includes sections on DNA vaccine design and enhancement, delivery .
The field of DNA vaccines has undergone explosive growth in the last few years. As usual, some historical precursors of this approach can be d- cerned in the scientific literature of the last decades. However, the present state of affairs appears to date from observations made discreetly in . Buy a cheap copy of DNA Vaccines book. The Wistar Institute, Philadelphia, PA. Text details the immunological mechanisms governing immune responses to vector encoded antigens. Also covers the use of DNA Free shipping over $ 1. Why use genetic vaccines? DNA vaccination has become the fastest growing field in vaccine technology following reports at the beginning of the 90’s that plasmid DNA induces an immune response to the plasmid-encoded antigen [1,2].This unexpectedly successful new method is considered by some to be one of the most important discoveries in the history of Cited by: In some cases, DNA vaccines have proven more immunogenic than other recombinant delivery systems (for example, recombinant vaccinia viruses, see ref. 99), and sometimes they appear to overcome a host's previous nonresponsiveness to a particular antigen. As a rule, DNA vaccines appear to induce better CD8 T cell responses than antibody Cited by: 3.